I am a research assistant for the Borrill group. My role is to ensure the smooth running of the lab, whilst also carrying out my own project(s).
I am currently involved in two separate projects: one investigating compensatory mechanisms of gene expression in wheat; and the second studying the effect of knocking-out (by gene editing) a transcription factor involved in senescence.
Prior to joining the Borrill group, I worked on various projects and plant species over seventeen years at the John Innes Centre. Notably, in Prof. Graham Moore’s group, I carried out projects on the PH1 locus and the KR1 crossability locus in wheat, and on the Gametocidal genes from the wild relative Aegilops sharonensis.
Zuo Z., Roux M.E., Chevalier J.R., Dagdas Y.F., Yamashino T., Højgaard S.D., Knight E., Østergaard L. & Petersen M. (2020). mRNA decapping machinery targets LBD3/ASL9 transcripts to authorize developmental reprogramming in Arabidopsis. BioRxiv. doi: https://doi.org/10.1101/834465
Grewal S., Gardiner L-J., Ndreca B., Knight E., Moore G., King I., King J. (2017) Comparative Mapping and Targeted-Capture Sequencing of the Gametocidal Loci in Aegilops sharonensis. The Plant Genome. doi: 10.3835/plantgenome2016.09.0090
Knight E., Binnie A. C., Draeger T., Moscou M. D., Rey M. D., Sucher J., Mehra S., King I., Moore G.(2015) Mapping the ‘breaker’ element of the gametocidal locus proximal to a block of sub-telomeric heterochromatin on the long arm of chromosome 4Ssh of Aegilops sharonensis. Theoretical and Applied Genetics. doi: 10.1007/s00122-015-2489-x
Knight E., Greer E., Draeger T., Thole V., Reader S., Shaw P., Moore G. (2010) Inducing chromosome pairing through premature condensation: analysis of wheat interspecific hybrids. Functional and Integrative Genomics. doi: 10.1007/s10142-010-0185-0
Bertin I., Fish L., Foote T. N., Knight E., Snape J. W., Moore G. (2009) Development of consistently crossable wheat genotypes for alien wheat gene transfer through fine mapping of the KR1 locus. Theoretical and Applied Genetics. doi: 10.1007/s00122- 009-1141-z
Al-Kaff N., Knight E., Bertin I., Foote T., Hart N., Griffiths S., & Moore G. (2007). Detailed dissection of the chromosomal region containing the PH1 locus in wheat Triticum aestivum: With deletion mutants and expression profiling. Ann. Bot. doi: 10.1093/aob/mcm252